Annual report pursuant to Section 13 and 15(d)

Accrued Expenses - Schedule of Accrued Expenses (Details)

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Accrued Expenses - Schedule of Accrued Expenses (Details) - USD ($)
Dec. 31, 2017
Dec. 31, 2016
Payables and Accruals [Abstract]    
Accrued clinical operations and trials costs $ 2,003,799 $ 1,647,490
Accrued product development costs 1,255,439 713,426
Accrued compensation 1,335,672 778,250
Accrued other 146,609 117,289
Total $ 4,741,519 $ 3,256,455