December 31,

2021

2020

Accrued clinical operations and trials costs

$

5,435,464

 $

14,132,842

Accrued product development costs

203,676

2,189,047

Accrued compensation

2,715,368

4,222,594

Accrued other

1,738,804

1,460,949

Total

$

10,093,312

 $

22,005,432