Annual report pursuant to Section 13 and 15(d)

WARRANTS (Details Narrative)

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WARRANTS (Details Narrative) - USD ($)
 12 Months Ended
Oct. 16, 2020
Jul. 28, 2020
Dec. 31, 2021
Dec. 31, 2020
New Accounting Pronouncements or Change in Accounting Principle [Line Items]        
Issuance of common stock upon exercise of stock options, shares     838,600 427,611
Debt face amount     $ 20,000,000  
Warrant [Member]        
New Accounting Pronouncements or Change in Accounting Principle [Line Items]        
Warrants to purchase shares of common stock, exercised     0 0
Share-based Payment Arrangement, Tranche One [Member]        
New Accounting Pronouncements or Change in Accounting Principle [Line Items]        
Debt face amount   $ 20,000,000    
CFF Warrant [Member]        
New Accounting Pronouncements or Change in Accounting Principle [Line Items]        
Warrants outstanding to purchase of common stock shares     1,000,000  
Exercise price of warrants     $ 13.20  
Number of warrants exercisable for common stock     500,000  
Investment Agreement [Member] | CFF Warrant [Member]        
New Accounting Pronouncements or Change in Accounting Principle [Line Items]        
Warrants outstanding to purchase of common stock shares     1,506,206  
Exercise price of warrants     $ 9.46  
Weighted average remaining life of warrants     3 years 7 months 6 days  
Number of warrants exercisable for common stock     500,000  
Warrant expire date     Jan. 26, 2025  
Fair value of warrants issued     $ 6,215,225  
Loan Agreement [Member] | K2 HealthVentures LLC [Member]        
New Accounting Pronouncements or Change in Accounting Principle [Line Items]        
Exercise price of warrants   $ 6.96    
Warrants to purchase shares of common stock, exercised   86,206    
Loan Agreement [Member] | K2 Warrant [Member]        
New Accounting Pronouncements or Change in Accounting Principle [Line Items]        
Warrants outstanding to purchase of common stock shares   86,206    
Exercise price of warrants   $ 6.96    
Warrants to purchase shares of common stock, exercised   86,206    
Warrant expire date   Jul. 28, 2030    
Fair value of warrants issued   $ 472,409    
Loan Agreement [Member] | K2 Warrant [Member] | Maximum [Member]        
New Accounting Pronouncements or Change in Accounting Principle [Line Items]        
Debt face amount   $ 50,000,000    
Professional Services Agreement [Member] | Warrant [Member] | Investor Relations Service Provider [Member]        
New Accounting Pronouncements or Change in Accounting Principle [Line Items]        
Warrants outstanding to purchase of common stock shares 420,000      
Exercise price of warrants $ 1.07      
Fair value of warrants issued $ 334,740