March 31,
2022

December 31,
2021

Accrued clinical operations and trials costs

$

2,132,865

$

5,435,464

Accrued product development costs

7,788

203,676

Accrued compensation

1,549,871

2,715,368

Accrued administrative costs

1,198,396

1,213,699

Accrued interest

607,486

525,105

Total

$

5,496,406

$

10,093,312