September 30,
2022

December 31,
2021

Accrued pre-clinical and clinical costs

$

1,405,142

$

5,435,464

Accrued product development costs

34,262

203,676

Accrued compensation

1,707,393

2,715,368

Accrued administrative costs

721,500

1,213,699

Accrued interest

965,542

525,105

Total

$

4,833,839

$

10,093,312