Annual report pursuant to Section 13 and 15(d)

Consolidated Statements of Cash Flows

v3.22.4
Consolidated Statements of Cash Flows - USD ($)
12 Months Ended
Dec. 31, 2022
Dec. 31, 2021
Cash flows from operating activities:    
Net loss $ (42,346,903) $ (45,640,426)
Adjustments to reconcile net loss to net cash used in operating activities:    
Stock-based compensation expense 5,719,637 9,480,373
Depreciation and amortization 762,995 999,817
Loss on impairment of fixed assets   606,078
Net amortization on premium of investments 124,875 698,254
Stock consideration in connection with PRI License Agreement   250,000
Loss on foreign exchange 648,520 342,424
Operating lease right of use asset amortization 724,858 639,415
Amortization of debt discount 742,478 700,613
Realized loss on investments 178,222  
Change in fair value of derivative liability (96,842) (663,290)
Loss on sale of property and equipment 21,235 99,520
Changes in operating assets and liabilities:    
Decrease in prepaid expenses 1,573,394 1,347,851
Decrease in contract asset   1,618,296
(Increase) decrease in other assets (108,961) 187,652
Decrease in accounts payable (256,835) (5,956,297)
Decrease in accrued expenses (4,094,160) (11,912,120)
Increase in other long-term liabilities   22,205
Decrease in operating lease liabilities (1,136,948) (1,004,062)
Net cash used in operating activities (37,544,435) (48,183,697)
Cash flows from investing activities:    
Purchases of investments (86,341,894) (87,266,596)
Proceeds from sales and maturities of investments 116,421,376 13,880,343
Purchases of property and equipment (13,449) (54,172)
Proceeds from sale of property and equipment 8,100 23,900
Net cash used in investing activities 30,074,133 (73,416,525)
Cash flows from financing activities:    
Proceeds from issuance of notes payable 452,250 984,375
Repayment of short-term borrowings (866,865) (926,595)
Proceeds from issuance of long-term borrowings 1,381,729
Repayment of long-term borrowings (1,500,729)
Proceeds from issuance of common stock 62,586,070
Issuance costs paid for common stock financings (1,820,437)
Net cash provided by financing activities (533,615) 60,823,413
Net increase (decrease) in cash, cash equivalents, and restricted cash (8,003,917) (60,776,809)
Cash, cash equivalents, and restricted cash at beginning of the period 25,676,532 86,453,341
Cash, cash equivalents, and restricted cash at end of the period 17,672,615 25,676,532
Supplemental disclosure of cash flow information and non cash transactions:    
Cash paid during the period for interest $ 1,969,583 1,740,878
Write-off of fully depreciated property and equipment   $ 544,752