Annual report pursuant to Section 13 and 15(d)

STOCK OPTIONS - SUMMARY OF OPTION ACTIVITY (Details)

v3.22.4
STOCK OPTIONS - SUMMARY OF OPTION ACTIVITY (Details) - USD ($)
12 Months Ended
Dec. 31, 2022
Dec. 31, 2021
Share-Based Payment Arrangement [Abstract]    
Shares, Outstanding, Beginning balance 510,870 476,321
Granted 185,169 245,793
Shares, Exercised   (27,953)
Shares, Forfeited or canceled (56,019) (182,655)
Shares, Expired (22,024) (636)
Shares, Outstanding, Ending balance 617,996 510,870
Shares, Exercisable 358,611  
Shares, Vested and expected to vest 584,143  
Weighted Average Exercise Price, Outstanding, Beginning balance $ 121.90 $ 154.50
Weighted Average Exercise Price, Granted 12.90 70.80
Weighted Average Exercise Price, Exercised   33.90
Weighted Average Exercise Price, Forfeited 107.13 151.20
Weighted Average Exercise Price , Expired 166.53 209.10
Weighted Average Exercise Price, Outstanding, Ending balance 88.99 $ 121.90
Weighted Average Exercise Price, Exercisable 125.97  
Weighted Average Exercise Price, Vested and expected to vest $ 92.55  
Weighted Average Remaining Contractual Term in Years, Outstanding 6 years 9 months 10 days  
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Outstanding, Weighted Average Exercise Price $ 92.55  
Weighted Average Remaining Contractual Term in Years, Vested 5 years 4 months 13 days  
Weighted Average Remaining Contractual Term in Years, Vested and expected to vest 6 years 7 months 28 days  
Average Intrinsic Value, Outstanding $ 11,195,964  
Shares, Vested and expected to vest 584,143  
Average Intrinsic Value, Vested $ 3,177,014  
Aggregate Intrinsic Value, Vested and expected to vest $ 9,969,530