Annual report pursuant to Section 13 and 15(d)

WARRANTS (Details Narrative)

v3.22.4
WARRANTS (Details Narrative) - USD ($)
 12 Months Ended
Oct. 16, 2020
Jul. 28, 2020
Dec. 31, 2022
Dec. 31, 2021
New Accounting Pronouncements or Change in Accounting Principle [Line Items]        
Issuance of common stock upon exercise of stock options, shares       27,953
Debt face amount     $ 20,000,000 $ 20,000,000
Warrant [Member]        
New Accounting Pronouncements or Change in Accounting Principle [Line Items]        
Warrants to purchase shares of common stock, exercised     0 0
Share-Based Payment Arrangement, Tranche One [Member]        
New Accounting Pronouncements or Change in Accounting Principle [Line Items]        
Debt face amount   $ 20,000,000    
CFF Warrant [Member]        
New Accounting Pronouncements or Change in Accounting Principle [Line Items]        
Class of Warrant or Right, Number of Securities Called by Warrants or Rights     33,334  
Exercise price of warrants     $ 396  
Warrant exercisable price per share     $ 396  
Investment Agreement [Member] | CFF Warrant [Member]        
New Accounting Pronouncements or Change in Accounting Principle [Line Items]        
Class of Warrant or Right, Number of Securities Called by Warrants or Rights     50,207  
Exercise price of warrants     $ 283.81  
Warrants to purchase shares of common stock, exercised     16,667  
Warrant exercisable price per share     $ 283.81  
Weighted average remaining life of warrants     2 years 7 months 6 days  
Number of warrants exercisable for common stock     16,667  
Warrant expire date     Jan. 26, 2025  
Fair Value Adjustment of Warrants     $ 6,215,225  
Loan Agreement [Member] | K2 HealthVentures LLC [Member]        
New Accounting Pronouncements or Change in Accounting Principle [Line Items]        
Exercise price of warrants   $ 208.80    
Warrants to purchase shares of common stock, exercised   2,874    
Warrant exercisable price per share   $ 208.80    
Loan Agreement [Member] | K2 Warrant [Member]        
New Accounting Pronouncements or Change in Accounting Principle [Line Items]        
Class of Warrant or Right, Number of Securities Called by Warrants or Rights   2,874    
Exercise price of warrants   $ 208.80    
Warrants to purchase shares of common stock, exercised   2,874    
Warrant exercisable price per share   $ 208.80    
Warrant expire date   Jul. 28, 2030    
Fair Value Adjustment of Warrants   $ 472,409    
Loan Agreement [Member] | K2 Warrant [Member] | Maximum [Member]        
New Accounting Pronouncements or Change in Accounting Principle [Line Items]        
Debt face amount   $ 50,000,000    
Professional Services Agreement [Member] | Warrants [Member] | Investor Relations Service Provider [Member]        
New Accounting Pronouncements or Change in Accounting Principle [Line Items]        
Class of Warrant or Right, Number of Securities Called by Warrants or Rights 14,000      
Exercise price of warrants $ 32.10      
Warrant exercisable price per share $ 32.10      
Fair Value Adjustment of Warrants $ 334,740