Annual report pursuant to Section 13 and 15(d)

Cover
- Document and Entity Information
Financial Statements
Notes to Financial Statements
Accounting Policies
- Significant Accounting Policies (Policies)
Notes Tables
Notes Details

Income Taxes (Details Narrative)

v3.8.0.1

Income Taxes (Details Narrative) - USD ($)		12 Months Ended
Income Taxes (Details Narrative) - USD ($)	Dec. 22, 2017	Dec. 31, 2017	Dec. 31, 2016	Dec. 31, 2015
Income Taxes [Line Items]
Net operating loss carryforwards		$ 56,536,000	$ 28,644,000
Net operating loss carryforwards excess stock-based compensation		1,432,000
Deferred tax assets valuation allowance increase		5,088,343	7,860,985
Uncertain tax position		$ 0	$ 0
Taxable income percentage		0.00%	0.00%	0.00%
Massachusett [Member]
Income Taxes [Line Items]
Net operating loss carryforwards		$ 53,110,000	$ 26,573,000
Research [Member]
Income Taxes [Line Items]
Tax credit carryforwards		$ 1,283,000	$ 736,000
Federal [Member]
Income Taxes [Line Items]
Operating loss carryforwards expiration year		2029
State And Local Jurisdiction [Member]
Income Taxes [Line Items]
Operating loss carryforwards expiration year		2014
The Tax Cut and Jobs Act of 2017 [Member]
Income Taxes [Line Items]
Taxable income percentage		80.00%
Deferred tax asset		$ 7,815,832
The Tax Cut and Jobs Act of 2017 [Member] \| Interest Expense [Member]
Income Taxes [Line Items]
Reduction of corporate tax rate percentage	30.00%
The Tax Cut and Jobs Act of 2017 [Member] \| Maximum [Member]
Income Taxes [Line Items]
Reduction of corporate tax rate percentage	35.00%
The Tax Cut and Jobs Act of 2017 [Member] \| Minimum [Member]
Income Taxes [Line Items]
Reduction of corporate tax rate percentage	21.00%
The Tax Cut and Jobs Act of 2017 [Member] \| Orphan Drug Credit [Member] \| Maximum [Member]
Income Taxes [Line Items]
Reduction of corporate tax rate percentage	50.00%
The Tax Cut and Jobs Act of 2017 [Member] \| Orphan Drug Credit [Member] \| Minimum [Member]
Income Taxes [Line Items]
Reduction of corporate tax rate percentage	25.00%

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