Quarterly report pursuant to Section 13 or 15(d)

Condensed Consolidated Statement of Stockholders' Equity (Unaudited)

Condensed Consolidated Statement of Stockholders' Equity (Unaudited) - USD ($)	Common Stock [Member]	Additional Paid-in Capital [Member]	Accumulated Deficit [Member]	Total
Balance at Dec. 31, 2017	$ 5,560	$ 123,476,102	$ (65,698,101)	$ 57,783,561
Balance, shares at Dec. 31, 2017	55,603,427
Issuance of common stock, net of issuance costs	$ 150	11,235,170		$ 11,235,320
Issuance of common stock, net of issuance costs, shares	1,500,000
Stock-based compensation expense		5,659,928		5,659,928
Issuance of common stock upon exercise of warrants	$ 1	4,999		5,000
Issuance of common stock upon exercise of warrants, shares	5,000
Issuance of common stock upon exercise of stock options	$ 13	337,632		337,645
Issuance of common stock upon exercise of stock options, shares	129,069
Fair value of warrant issued in connection with Investment Agreement		6,215,225		6,215,225
Net loss			(38,365,947)	(38,365,947)
Balance at Sep. 30, 2018	$ 5,724	146,929,056	(104,064,048)	42,870,732
Balance, shares at Sep. 30, 2018	57,237,496
Balance at Jun. 30, 2018	$ 5,719	144,942,278	(89,462,837)	55,485,160
Balance, shares at Jun. 30, 2018	57,192,496
Stock issuance costs		(11,512)		(11,512)
Stock-based compensation expense		1,958,917		1,958,917
Issuance of common stock upon exercise of warrants	$ 1	4,999		5,000
Issuance of common stock upon exercise of warrants, shares	5,000
Issuance of common stock upon exercise of stock options	$ 4	34,374		34,378
Issuance of common stock upon exercise of stock options, shares	40,000
Net loss			(14,601,211)	(14,601,211)
Balance at Sep. 30, 2018	$ 5,724	146,929,056	(104,064,048)	42,870,732
Balance, shares at Sep. 30, 2018	57,237,496
Balance at Dec. 31, 2018	$ 5,725	$ 148,888,635	$ (121,370,240)	$ 27,524,120
Balance, shares at Dec. 31, 2018	57,247,496
Issuance of common stock, net of issuance costs	$ 620	$ 37,718,078		$ 37,718,698
Issuance of common stock, net of issuance costs, shares	6,198,500
Stock-based compensation expense		8,884,001		8,884,001
Issuance of common stock upon exercise of warrants	$ 112	(112)
Issuance of common stock upon exercise of warrants, shares	1,119,868
Issuance of common stock upon exercise of stock options	$ 10	$ 386,801		$ 386,811
Issuance of common stock upon exercise of stock options, shares	107,029			107,029
Net loss			$ (44,872,957)	$ (44,872,957)
Balance at Sep. 30, 2019	$ 6,467	195,877,403	(166,243,197)	29,640,673
Balance, shares at Sep. 30, 2019	64,672,893
Balance at Jun. 30, 2019	$ 6,465	$ 192,819,731	$ (145,452,396)	$ 47,373,800
Balance, shares at Jun. 30, 2019	64,644,093
Stock-based compensation expense		$ 2,977,574		$ 2,977,574
Issuance of common stock upon exercise of stock options	$ 2	80,098		80,100
Issuance of common stock upon exercise of stock options, shares	28,800
Net loss			(20,790,801)	(20,790,801)
Balance at Sep. 30, 2019	$ 6,467	$ 195,877,403	$ (166,243,197)	$ 29,640,673
Balance, shares at Sep. 30, 2019	64,672,893